Blood-C, is a 2011 anime/manga series and 2012 film produced and collaborated by Studio Production I.G and manga creators CLAMP. This is Production I.G's second anime series related to the Blood franchise, the first being Blood+, which aired in 2005–2006.
Saya Kisaragi is a normal girl who is overly clumsy and kind. She lives with her father, the head of a shrine, and learns the 'art of the sword' from him. When she is faced with various forms of 'trials' that test her kindness, it brings misfortune for being 'overly-kind'. Against misfortune and for the sake of her friends, she maintains her kind heart and becomes stronger. However, in her journey, how will she fare, why is she being tested?
The anime was announced in the May 2011 issue of Shōnen Ace magazine where it was revealed it will be a collaboration between Studio Production I.G and the manga creator group CLAMP where CLAMP will be creating the story and original character designs while Production I.G will be handling the animation. The anime is published by Aniplex and will be directed by Tsutomu Mizushima with Junichi Fujisaku, who previously worked on Blood the Last Vampire and Blood+, as creative supervisor. Nanase Ohkawa will be supervising the scripts and co-writing them with Fujisaku while Kazuchika Kise is adapting CLAMP's character designs for animation and Naoki Sato is composing the music. The opening theme is "spiral" performed by Ray Fujita's band DUSTZ, while the ending theme is "Junketsu Paradox" performed by Nana Mizuki. The anime aired on July 8, 2011 on MBS and TBS.(Via Wiki)